Free ATI TEAS 7 Science guide

October 2026 - Microorganisms & Disease Study Guide

Bacteria, viruses, fungi and parasites cause disease by different mechanisms, which is why antibiotics treat bacterial infections and do nothing at all against viruses. Sorting a pathogen into the right group is what most questions in this topic come down to.

Science guide Biology · 9 scored questions 6 min read
Representative bacteria, virus, fungus and protozoan above a circular chain of infection from pathogen and reservoir through exit, transmission, entry and susceptible host.
Pathogen groups differ structurally, but spread still requires a complete chain. Prevention works by breaking any link between the reservoir and a susceptible host.

The four groups

PathogenLiving cell?Treated withExamples
Bacteria Yes — single-celled prokaryotes Antibiotics Strep throat, tuberculosis, most urinary infections
Viruses No — genetic material in a protein coat Antivirals; mostly supportive care Influenza, chickenpox, the common cold, HIV
Fungi Yes — eukaryotes Antifungals Thrush, athlete's foot, ringworm
Parasites Yes — eukaryotes, living on or in a host Antiparasitics Malaria, tapeworm, lice

Why antibiotics do nothing against viruses

Antibiotics work by attacking structures and processes that bacteria have and human cells do not — a bacterial cell wall, bacterial ribosomes, bacterial enzymes. A virus has none of these. It is genetic material in a protein coat, and it reproduces by hijacking a host cell's machinery, which means there is nothing bacterial for the drug to target.

This is not a matter of dose or of the antibiotic being weak. There is no mechanism at all, which is why an antibiotic prescribed for a cold has no effect on the illness while still exposing bacteria elsewhere in the body to the drug.

Viruses are not considered living by most definitions: they cannot reproduce, metabolise or respond on their own. Everything a virus does happens inside a host cell using that cell's equipment.

Antibiotic resistance

A frequently tested application of natural selection.

  • A bacterial population varies. A few individuals happen to survive a given antibiotic.
  • The antibiotic kills the susceptible ones, leaving the survivors to reproduce.
  • The next generation is descended from survivors, so resistance becomes common.
  • The bacteria did not become resistant in response to the drug — resistant individuals were selected for. That distinction is the point of the question.

How infections spread

  • Direct contact — touching, including contaminated hands.
  • Droplet — coughs and sneezes over short distances.
  • Airborne — smaller particles that stay suspended and travel further.
  • Vehicle — contaminated food, water or equipment.
  • Vector — carried by another organism, as malaria is by mosquitoes.

Reasoning about a treatment decision

Worked example

A patient with a sore throat is found to have a viral infection. Why would an antibiotic not help, and what would it risk?

  1. Identify the pathogen type: viral.
  2. Recall the mechanism of antibiotics: they target bacterial structures.
  3. A virus has no cell wall, no bacterial ribosomes and no bacterial enzymes, so there is no target.
  4. Meanwhile the drug still reaches the bacteria that normally live in the body, selecting for resistant ones.

It cannot help, because there is nothing for it to act on — and it exposes the body's other bacteria to selection pressure, which is how resistance spreads.

Terms to know

Pathogen
An organism or agent that causes disease.
Bacterium
A single-celled prokaryote. Some are harmful, many are not.
Virus
Genetic material in a protein coat that reproduces only inside a host cell.
Fungus
A eukaryotic organism such as a yeast or mould.
Parasite
An organism living on or in a host at the host's expense.
Host
The organism a pathogen infects.
Antibiotic
A drug that kills or inhibits bacteria. Ineffective against viruses.
Antibiotic resistance
The survival and spread of bacteria that antibiotics no longer kill.
Vector
An organism that carries a pathogen from one host to another.
Normal flora
The harmless microorganisms that ordinarily live in and on the body.

What the TEAS asks most

The same core ideas appear in different wording. If you can answer these without stopping to think, you have what this section requires.

Which type of pathogen causes this disease?

Learn the examples in the table — most questions are a direct match.

Why will an antibiotic not treat this infection?

Because it is viral, and antibiotics act on bacterial structures a virus does not have.

How does antibiotic resistance develop?

By natural selection: resistant individuals survive and reproduce. Bacteria do not adapt in response to the drug.

How is this infection transmitted?

Match the route: contact, droplet, airborne, vehicle or vector.

Key points

  • Bacteria, viruses, fungi and parasites cause disease by different mechanisms.
  • Antibiotics target bacterial structures, so they cannot affect viruses.
  • Viruses are not living cells and reproduce only inside a host.
  • Resistance arises by natural selection, not by bacteria responding to the drug.
  • Transmission routes: contact, droplet, airborne, vehicle, vector.

Review quiz

4 questions on this topic, each with the reasoning worked through. Pick an answer to see how it went, or open the explanation straight away.

  1. Question 1 of 4

    Why are antibiotics ineffective against viral infections?

    Answer choices for question 1

    Show the answer and explanation

    Correct answer: B. Antibiotics target bacterial structures that viruses do not have.

    A virus has no cell wall, no bacterial ribosomes and no bacterial enzymes, so an antibiotic has nothing to act on. Speed and dose are irrelevant when no mechanism exists, and "resistant" is the wrong word — resistance describes bacteria that were once susceptible.

  2. Question 2 of 4

    Which of these conditions is caused by a fungus?

    Answer choices for question 2

    Show the answer and explanation

    Correct answer: C. Athlete's foot

    Athlete's foot is a fungal infection of the skin and is treated with antifungals. Influenza is viral, tuberculosis is bacterial, and malaria is caused by a parasite carried by mosquitoes — one from each of the other three groups.

  3. Question 3 of 4

    How does antibiotic resistance develop in a bacterial population?

    Answer choices for question 3

    Show the answer and explanation

    Correct answer: B. Bacteria that happen to survive reproduce, so their descendants dominate.

    This is natural selection: variation already exists, the drug removes the susceptible individuals, and the survivors pass on their resistance. Bacteria do not adapt on demand, and neither the drug nor the immune system is the thing that changes.

  4. Question 4 of 4

    Malaria is transmitted to humans by mosquitoes. What is the mosquito's role called?

    Answer choices for question 4

    Show the answer and explanation

    Correct answer: C. A vector

    An organism that carries a pathogen from one host to another is a vector. The pathogen itself is the parasite causing malaria, and the human is the host in whom the disease develops.

Put this TEAS topic into practice

Build a set on role of microorganisms in disease and use the rationale on every question to reinforce what you just reviewed.